Franchises for Sale in Missouri up to $450,000

HealthSource Chiropractic: $363K Avg Gross Profit with Unmatched Care Nationwide! More info

With $560,311 in Avg Gross Sales, Painter1 blends decades of experience with innovative, owner-focused improvements for streamlined success. More info

Whether you are looking to diversify your portfolio or expand as an experienced tree care professional, Monster Tree Service provides an exceptional business opportunity in the $36 billion tree care industry. More info

Average Gross Revenue of $572,394!* Own the #1 Ranked Tile and Grout Cleaning Business by Entrepreneur Magazine. More info

Groovy Hues, a HorsePower Brands company, is revolutionizing the $25 billion painting industry with cutting-edge technology. Providing both commercial and residential services such as interior/exterior painting, power washing, and gutter installation. More info

Set Your Own Hours & Control Your Financial Destiny—Start a Mobile Tool Franchise With 1,900+ Stores Earning an Average Revenue of Over $491K More info

ANY LAB TEST Now® is the nation's first retail, direct access lab testing company that offers thousands of lab test in one place. If you are interested in owning a business that allows consumers to take control of their health. Any Lab Test may for you. More info

Join the #1 childcare franchise! More info

Recognized in the 2026 Entrepreneur Franchise 500, Homewatch CareGivers is a recession resilient in-home care franchise where owners average $2,552,023** in gross revenue while building meaningful, impact driven usinesses. -resilient in-home care franchise where owners average $2,552,023-driven businesses. More info

We are the largest Take 'N' Bake Pizza franchise, offering simple operations and award winning pizza! More info

QSR Multi-Unit Franchise Opportunity More info

Lightbridge Academy® stands out in the child care and early education segment with their technology, curriculum, business model, training and support. More info

Movers Who Care - Own a market leading business with $3.1M Average Unit Sales More info

Mosquito Squad Plus is a leader in mosquito and pest control, built around simple systems and ongoing support to help business owners enter the industry with clarity and confidence. More info

With Shipley Do-Nuts, you’re not just selling treats—you’re investing in a proven system that’s been making life delicious for nearly 90 years. More info

A cup of PJ’s Coffee is more than just coffee—it’s an experience along an exciting business opportunity for entrepreneurs. With over 193 locations across 15 U.S. states and two international markets, PJ’s is expanding fast, and we're looking for passionate partners to join us on this incredible growth journey. Multi-unit opportunities are available today in hot markets! Ready to brew success with PJ’s? More info

Patriot Pipeline: an industry leader in underground wet and dry utilities. Affiliate location profit of $4.100,838*. Markets available in: California, Florida, Georgia, Iowa, Idaho, Kansas, Kentucky, Maine, Missouri, Montana, New Hampshire, New Jersey, Nevada, Ohio, Oklahoma, Pennsylvania, Texas, Utah, Vermont, Wyoming More info

$1.2M+ AUV* Brunch is booming — and so are we. Scramblers blends modern growth with 35 years of proven success. Our market is forecast to grow at a CAGR of 6.8% from now through 2028. Now is your chance to eggsperience this incredible opportunity!! More info

Change lives through math, including your own - no educator experience required. We're top-in-category for franchisee satisfaction. More info

Want to be the best of the best? Joining Loyalty Business Brokers gives you the advantage over all the rest. Our Business Is Selling Your Business! More info

Join one of America's first franchises in commercial cleaning with 65+ years of experience in the industry. Low startup capital and high earning potential upwards of $1.97M in average gross sales. More info

Join a leading disaster restoration franchise with high franchise earnings upwards of $2.49M in average gross sales and over 65+ years of experience in the industry. More info

Since 2002, ASP has been a leader in the pool service industry, offering reliable pool cleaning, maintenance, construction, and renovation services. This franchise offers strong support to help you start and grow your own business that is backed by a nationally recognized and trusted brand name – America’s Swimming Pool Company (ASP). More info

Sport Clips is a manager-style business model that’s designed for scalability to multiple units! With more than 30 years’ experience and culture at our core, join the leading men’s hair care brand today! More info