Franchises for Sale in South Dakota up to $450,000

Over $2 Million Average Gross Sales - As Low As $350,500 Investment & Recession-Safe More info

QC Kinetix is the only nonsurgical medical franchise that provides customized Regenerative Medicine treatments. More info

Transform Lives with 101 Mobility; Make Helping Others Your Business! More info

A trusted national leader in the disaster restoration industry More info

Sport Clips is a manager-style business model that’s designed for scalability to multiple units! With more than 30 years’ experience and culture at our core, join the leading men’s hair care brand today! More info

America's Small Market Alehouse! Be the one to bring our unique handcrafted food, 40 taps, a family friendly sports experience (and sales and profits) to your town! More info

Merry Maids is a recognized and industry-leading house cleaning franchise in the U.S. Merry Maids has more than 7,000 home cleaning professionals who service homes on four continents, including more than 200,000 homes in North America every month. Merry Maids is proud to be part of Atlanta-based ServiceMaster Global Holdings, Inc. (NYSE: SERV), a leading provider of essential residential and commercial services for over 75 years. More info

DUCTZ provides industry-leading air duct cleaning, dryer vent cleaning, and HVAC restoration services for residential and commercial properties. More info

Snapology is a leading children’s enrichment franchise focused on STEAM (Science, Technology, Engineering, Arts, and Math) education through hands-on, play-based learning. With programs that engage kids ages 4–14 through robotics, coding, animation, and themed building activities, Snapology makes learning fun and impactful. The mobile-friendly model offers flexibility and low overhead, making it an ideal opportunity for passionate entrepreneurs looking to bring meaningful educational experiences to their communities. Whether hosted in schools, community centers, or birthday parties, Snapology helps children build confidence, critical thinking skills, and a lifelong love of learning. More info

Whether full-time or part-time, Mattress By Appointment is your easiest pathway to get out of your suit/tie 60 hour work week while earning more money! More info

Ranked as a top Junk-Removal Services franchise by 2026 Entrepreneur Franchise 500®. $553K average gross sales!* More info

Become a SiteSwan Website Reseller and earn money building and selling websites to local businesses in your area. More info

Average Gross Sales of $461,941!* Award-winning MaidPro is America’s most loved home cleaning franchise. Trusted for over 30 years by families and businesses alike. More info

Empower Lives with Assisted Living Locators. Thriving Home-Based Referral and Placement Franchise. Discover Lucrative Opportunities for Business Success Today! More info