Healthcare & Senior Care Franchises for Sale in Missouri up to $300,000

Open Your Own ABA Clinic: Make a Difference While Building a Profitable Business. At SOS Franchising, we empower aspiring entrepreneurs to launch successful Applied Behavior Analysis (ABA) therapy centers that serve children with autism. More info

MaxStrength Fitness provides 1-on-1 training, improving strength and overall health to active agers in a calm, private environment with science-based workouts designed for efficiency and results. More info

HealthSource Chiropractic: $363K Avg Gross Profit with Unmatched Care Nationwide! More info

Blue Moon Estate Sales is a top-ranked franchise that strikes all the right chords with people looking to build on their success and make a difference in others' lives. More info

ANY LAB TEST Now® is the nation's first retail, direct access lab testing company that offers thousands of lab test in one place. If you are interested in owning a business that allows consumers to take control of their health. Any Lab Test may for you. More info

Recognized in the 2026 Entrepreneur Franchise 500, Homewatch CareGivers is a recession resilient in-home care franchise where owners average $2,599,498** in gross revenue while building meaningful, impact driven businesses. More info

FYZICAL is the largest Physical Therapy franchise in the U.S. Their unique Balance & Fall Prevention Program differentiates them. No medical experience required. More info

Aircraft and Cleaning, Reconditioning & Protection - A Low Cost Franchise in the exciting world of Aviation Detailing More info

For more than 20 years, Cruise Planners has been a low-cost franchise opportunity that can yield high returns! More info

With $1,432,614 in avg revenue and $635,523 in net operating income, this youth sports franchise pairs HUGE revenue potential with passion More info

Starting your own business. The American dream. The opportunities are endless. And with Mac Tools – you’ll have a built-in support network to help make your dream a reality. With a Mac Tools franchise, we provide everything you need to get on the right path. More info

We are the largest and fastest growing kids coding and stem concept in the world! With low start-up costs, a proven business model, best-in-class support across operations, technology, curriculum, and marketing, plus proprietary curriculum and products, Code Ninjas is the premier option in the youth enrichment business. More info

Ace Handyman Services, owned by Ace Hardware, is a home services business that focuses on solving customer's small to large size handyman projects in the home and commercial space. More info