Healthcare & Senior Care Franchises for Sale in South Dakota up to $350,000

ANY LAB TEST Now® is the nation's first retail, direct access lab testing company that offers thousands of lab test in one place. If you are interested in owning a business that allows consumers to take control of their health. Any Lab Test may for you. More info

Nation's largest assisted living/memory care franchise! 200+ locations in 20 states and growing. Come join 35+ years of experience! More info

Recognized in the 2026 Entrepreneur Franchise 500, Homewatch CareGivers is a recession resilient in-home care franchise where owners average $2,552,023** in gross revenue while building meaningful, impact driven usinesses. -resilient in-home care franchise where owners average $2,552,023-driven businesses. More info

Transform Lives with 101 Mobility; Make Helping Others Your Business! More info

Mint Condition is an award-winning, best-in-class commercial cleaning franchise system designed for entrepreneurs ready to acquire and develop a scalable business asset. More info

20 Years as America's Leader in Medical Billing with Unparallelled Training, and Support. 100k Potential, Work From Anywhere, Full-Time or Part-Time. Come Join Our Success! More info

Leading Residential Property Management Franchise Seeking Like Minded Candidates. We provide an opportunity in Property Mgmt for those seeking a residual income and the lifestyle that accompanies it. More info

Starting your own business. The American dream. The opportunities are endless. And with Mac Tools – you’ll have a built-in support network to help make your dream a reality. With a Mac Tools franchise, we provide everything you need to get on the right path. More info

With nearly 600 centers across North America, AAMCO is actively seeking single and multi-unit franchise owners. AAMCO is known for providing higher quality of service and seeking those who share that commitment. Take advantage of a world-wide brand built on decades of consumer trust and loyalty. The day you open your doors, the community already knows your reputation for reliable, expert automotive care. As the noted leader in transmission repair, you are positioned for success within the lucrative and complex vehicle services industry. More info

The Little Gym is the world’s premier enrichment and physical development center for children ages 4 months to 12 years. Backed by decades of success and a globally recognized brand, The Little Gym franchise empowers owners to help kids build confidence, motor skills, and social-emotional strength through movement-based learning and gymnastics. With a loyal customer base, multiple revenue streams, and comprehensive support, franchisees are well-equipped to grow a meaningful business that positively impacts lives. More info