Healthcare & Senior Care Franchises for Sale in South Carolina

Built for Owners Who Want to Win. Home Helpers operates in one of Entrepreneur's Top 5 most profitable franchise sectors — and owner validation proves it. Talk to existing franchisees and you'll hear the same thing: the support is real, the model works, and they'd do it again. The differentiator is the Cared-4 program — total care covering in-home services, technology, wellness and nutrition that no competitor matches. Four profit centers. 29+ years of continuous growth. And a leadership team that stays with you past the opening. If you're evaluating home care franchises, start here. More info

Sweat440 is flipping the fitness industry on its head. With 40-minute classes starting every 10 minutes, members get unbeatable convenience—and franchise owners see powerful returns. Current locations historically have generated strong six-figure revenues with scalable growth opportunities, making Sweat440 a high-energy business built for maximum ROI. More info

Blue Moon Estate Sales is a top-ranked franchise that strikes all the right chords with people looking to build on their success and make a difference in others' lives. More info

Open Your Own ABA Clinic: Make a Difference While Building a Profitable Business. At SOS Franchising, we empower aspiring entrepreneurs to launch successful Applied Behavior Analysis (ABA) therapy centers that serve children with autism. More info

HealthSource Chiropractic: $363K Avg Gross Profit with Unmatched Care Nationwide! More info

FYZICAL is the largest Physical Therapy franchise in the U.S. Their unique Balance & Fall Prevention Program differentiates them. No medical experience required. More info

Ranked as a top Home Inspections franchise by 2026 Entrepreneur Franchise 500®. $273K median gross sales for 2-unit owners!* More info

Starting your own business. The American dream. The opportunities are endless. And with Mac Tools – you’ll have a built-in support network to help make your dream a reality. With a Mac Tools franchise, we provide everything you need to get on the right path. More info

Once Upon A Child buys and sells gently used and new children's clothing, toys, equipment and more! With over 415 stores open in North America we are the nations largest chain of children's resale stores. More info

Dumpster Dudez - Choose Orange. Choose the Best. Choose Dumpster Dudez! More info

Become a SiteSwan Website Reseller and earn money building and selling websites to local businesses in your area. More info

With an average ticket of $12,538 and $8.4 MILLION in total income, this bathroom transformation franchise is the NEXT BIG THING in franchising. More info