Multi Unit Franchises for Sale in South Dakota up to $350,000

Breakfast, Lunch, Brunch... All at Once! A fresh, community-driven franchise with strong returns and a guest-first culture. More info

The Neighborhood's Healthiest Lawn® More info

HealthSource Chiropractic: $363K Avg Gross Profit with Unmatched Care Nationwide! More info

Hello Sugar dominates the Hair Removal category by offering the trifecta: wax, sugar, & laser hair removal! Our innovative approach to technology and franchisor services reduces franchisee workload and oversight requirements allowing you to scale without the need to work long nights in the business. More info

Art of Drawers is the premier brand for custom kitchen organization. We design & install custom, pull out drawers that retrofit into existing cabinets to create more space, accessibility and organization for our customer. More info

Average Gross Revenue of $572,394!* Own the #1 Ranked Tile and Grout Cleaning Business by Entrepreneur Magazine. More info

If you have been feeling the need for a professional change that offers flexibility, growth potential, and personal fulfillment, Clothes Mentor franchise ownership might be the path you have been searching for. The resale industry is booming, and franchising has real advantages, but the best part is the process is already nailed down for you. More info

Groovy Hues, a HorsePower Brands company, is revolutionizing the $25 billion painting industry with cutting-edge technology. Providing both commercial and residential services such as interior/exterior painting, power washing, and gutter installation. More info

Mosquito Hunters-Pest Hunters-Humbug Holiday Lighting or as we like to say Hunters-Humbug is a cutting edge 3-in-1 business model that is rapidly swarming the country. This is an opportunity to join a leader in the home services space and the only franchise that offers 3 distinct revenue streams that provides complimentary services ranging from mosquito, tick and flea abatement to full service pest control, along with holiday lighting services. Join a growing franchise system that features multiple service lines and revenue streams, recurring revenue, and high customer retention, along with low monthly overhead and high margins. Keep employees and customers year-round, and differentiate yourself from the competition, with our 3 in 1 model! More info

Whether you are looking to diversify your portfolio or expand as an experienced tree care professional, Monster Tree Service provides an exceptional business opportunity in the $36 billion tree care industry. More info

ANY LAB TEST Now® is the nation's first retail, direct access lab testing company that offers thousands of lab test in one place. If you are interested in owning a business that allows consumers to take control of their health. Any Lab Test may for you. More info

Recognized in the 2026 Entrepreneur Franchise 500, Homewatch CareGivers is a recession resilient in-home care franchise where owners average $2,552,023** in gross revenue while building meaningful, impact driven usinesses. -resilient in-home care franchise where owners average $2,552,023-driven businesses. More info

Nation's largest assisted living/memory care franchise! 200+ locations in 20 states and growing. Come join 35+ years of experience! More info

America's Small Market Alehouse! Be the one to bring our unique handcrafted food, 40 taps, a family friendly sports experience (and sales and profits) to your town! More info

Merry Maids is a recognized and industry-leading house cleaning franchise in the U.S. Merry Maids has more than 7,000 home cleaning professionals who service homes on four continents, including more than 200,000 homes in North America every month. Merry Maids is proud to be part of Atlanta-based ServiceMaster Global Holdings, Inc. (NYSE: SERV), a leading provider of essential residential and commercial services for over 75 years. More info