1. Franchise Directory
  2. Business Opportunities in South Carolina over $500,000

Business Opportunities for Sale in South Carolina over $500,000

Browse our selection of South Carolina business opportunities for sale over $500,000. For more information on these business opportunities in South Carolina, add business opportunities to your free info list, provide contact information, and press the Get Information button. Thank you for starting your search for a business opportunity with BizQuest!

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No franchises matching your criteria were found, please consider these popular franchises seeking buyers in South Carolina.

Executive Home Care
Liquid Capital Required:
$75,000

Non Medical HomeCare Franchise Opportunity More info

MD Hyperbaric
Liquid Capital Required:
$150,000

Experience the Healing Power of Hyperbaric Oxygen Therapy Backed by Research Guided by Trained Professionals Focused on You More info

The Little Gym Child Fitness
Liquid Capital Required:
$100,000

The Little Gym is the world’s premier enrichment and physical development center for children ages 4 months to 12 years. Backed by decades of success and a globally recognized brand, The Little Gym franchise empowers owners to help kids build confidence, motor skills, and social-emotional strength through movement-based learning and gymnastics. With a loyal customer base, multiple revenue streams, and comprehensive support, franchisees are well-equipped to grow a meaningful business that positively impacts lives. More info

Aesthetic Development Group
Liquid Capital Required:
$13,500

Aesthetic Development Group is an affordable, turnkey business opportunity, offering body contouring and facial rejuvenation service lines to both new and established practices. More info

A Place At Home
Liquid Capital Required:
$50,000

Build a thriving senior care business with heart. Multiple revenue streams, award-winning support, and a mission that makes a difference. More info

Junk King
Liquid Capital Required:
$50,000

Ranked as a top Junk-Removal Services franchise by 2026 Entrepreneur Franchise 500®. $551K average gross sales!* More info

Healthy Smart Mart™
Liquid Capital Required:
$23,000

Micro markets are the future of break-rooms and these “automated convenience stores” are BOOMING! Key to your success is our growing brand recognition, training, and support. Not to mention that the Healthy Smart Mart™ proprietary payment kiosk and phone “app-based" payment system are cutting edge! More info

Ziggi's Coffee
Liquid Capital Required:
$150,000

Brew community and profit with Ziggi's Coffee-flexible formats, strong support, and high AUV in one of America's fastest-growing franchises. More info

American Business Systems
Liquid Capital Required:
$30,000

20 Years as America's Leader in Medical Billing with Unparallelled Training, and Support. 100k Potential, Work From Anywhere, Full-Time or Part-Time. Come Join Our Success! More info

Sticky Fingers Cooking
Liquid Capital Required:
$48,000

High-Margin. High-Impact. Start at ~$140K. Scale to $500K+. A proven path from startup to scale in the booming $50B+ children’s enrichment market. More info

Travelin’ Tom’s Coffee
Liquid Capital Required:
$20,000

Premium mobile coffee franchise from the makers of Kona Ice. Proven model, fixed royalties, and expert business support. Own your journey today! More info

Caring Transitions
Liquid Capital Required:
$50,000

75 million seniors need home relocation, downsizing, and estate sales services. Join one of America’s fastest-growing senior service franchises. More info

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