Retail Franchises for Sale in South Carolina over $500,000

Starting your own business. The American dream. The opportunities are endless. And with Mac Tools – you’ll have a built-in support network to help make your dream a reality. With a Mac Tools franchise, we provide everything you need to get on the right path. More info

Snapology is a leading children’s enrichment franchise focused on STEAM (Science, Technology, Engineering, Arts, and Math) education through hands-on, play-based learning. With programs that engage kids ages 4–14 through robotics, coding, animation, and themed building activities, Snapology makes learning fun and impactful. The mobile-friendly model offers flexibility and low overhead, making it an ideal opportunity for passionate entrepreneurs looking to bring meaningful educational experiences to their communities. Whether hosted in schools, community centers, or birthday parties, Snapology helps children build confidence, critical thinking skills, and a lifelong love of learning. More info

Ranked as a top Junk-Removal Services franchise by 2026 Entrepreneur Franchise 500®. $551K average gross sales!* More info

Experience the Healing Power of Hyperbaric Oxygen Therapy Backed by Research Guided by Trained Professionals Focused on You More info

Moe's Southwest Grill® is authentic, adventurous and all-around fun. Our passion has made us the go-to brand for Southwestern fare and one of the most recognized fast-casual Mexican restaurant franchises available. We're the ideal choice for franchise owners interested in building a loyal following in their market while embracing their own independent spirit. More info

Non Medical HomeCare Franchise Opportunity More info

Replace your income, or earn EXTRA INCOME and keep your job. Earn money 24/7 with HEALTHY VENDING. More info

Build a thriving senior care business with heart. Multiple revenue streams, award-winning support, and a mission that makes a difference. More info

75 million seniors need home relocation, downsizing, and estate sales services. Join one of America’s fastest-growing senior service franchises. More info

The Little Gym is the world’s premier enrichment and physical development center for children ages 4 months to 12 years. Backed by decades of success and a globally recognized brand, The Little Gym franchise empowers owners to help kids build confidence, motor skills, and social-emotional strength through movement-based learning and gymnastics. With a loyal customer base, multiple revenue streams, and comprehensive support, franchisees are well-equipped to grow a meaningful business that positively impacts lives. More info

If you’ve considered investing in a food franchise, our grazing board business could be right for you. Charcuterie boards have proven to be a food trend with staying power. More info

For more than 20 years, Cruise Planners has been a low-cost franchise opportunity that can yield high returns! More info