1. Franchise Directory
  2. Business Opportunities in South Dakota over $500,000

Business Opportunities for Sale in South Dakota over $500,000

Browse our selection of South Dakota business opportunities for sale over $500,000. For more information on these business opportunities in South Dakota, add business opportunities to your free info list, provide contact information, and press the Get Information button. Thank you for starting your search for a business opportunity with BizQuest!

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No franchises matching your criteria were found, please consider these popular franchises seeking buyers in South Dakota.

Aesthetic Development Group
Liquid Capital Required:
$13,500

Aesthetic Development Group is an affordable, turnkey business opportunity, offering body contouring and facial rejuvenation service lines to both new and established practices. More info

Healthier4U Vending
Liquid Capital Required:
$53,000

Are you passionate about owning your own business? Are you interested in giving people the choice to eat healthy? If the answer is yes, then you have found the right partner to build you a successful healthy vending business. At Healthier4U Vending we share your passion and want you to join us to give the choice to eat healthy to everyone. Come see how together we can change your life. More info

MARS Aviation Detailing
Liquid Capital Required:
$50,000

Aircraft and Cleaning, Reconditioning & Protection - A Low Cost Franchise in the exciting world of Aviation Detailing More info

Junk King
Liquid Capital Required:
$50,000

Ranked as a top Junk-Removal Services franchise by 2026 Entrepreneur Franchise 500®. $551K average gross sales!* More info

Mattress By Appointment
Liquid Capital Required:
$15,000

Whether full-time or part-time, Mattress By Appointment is your easiest pathway to get out of your suit/tie 60 hour work week while earning more money! More info

Snapology
Liquid Capital Required:
$50,000

Snapology is a leading children's enrichment franchise focused on STEAM (Science, Technology, Engineering, Arts, and Math) education through hands-on, play-based learning. With programs that engage kids ages 4-14 through robotics, coding, animation, and themed building activities, Snapology makes learning fun and impactful. The mobile-friendly model offers flexibility and low overhead, making it an ideal opportunity for passionate entrepreneurs looking to bring meaningful educational experiences to their communities. Whether hosted in schools, community centers, or birthday parties, Snapology helps children build confidence, critical thinking skills, and a lifelong love of learning. More info

ATC Healthcare Services
Liquid Capital Required:
$200,000

If you’ve got business savvy and a passion for helping others, ATC Healthcare Services offers a healthcare staffing agency to take your entrepreneurial spirit to new heights! More info

HouseMaster
Liquid Capital Required:
$25,000

Ranked as a top Home Inspections franchise by 2026 Entrepreneur Franchise 500®. $273K median gross sales for 2-unit owners!* More info

Pet Wants
Liquid Capital Required:
$50,000

Fresh pet food franchise in a $158B industry. Low investment, proven system, full support. Avg. revenue $546K. No experience needed. More info

H&H Bagels
Liquid Capital Required:
$500,000

New York City's most iconic bagel since 1972, now expanding nationwide. Major metropolitan areas are still available. More info

Menchie’s
Liquid Capital Required:
$120,000

Own a high-performing retail engine. Proven systems, consistent repeat traffic, and a brand built for long-term equity in a simplified category. More info

Caring Transitions
Liquid Capital Required:
$50,000

75 million seniors need home relocation, downsizing, and estate sales services. Join one of America's fastest-growing senior service franchises. More info

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