1. Franchise Directory
  2. Home Based Franchises in Missouri over $500,000

Home Based Franchises for Sale in Missouri over $500,000

Browse our selection of Missouri home based business opportunities and franchises for sale over $500,000. For more information on these home based opportunities in Missouri, add franchises to your free info list, provide contact information, and press the Get Information button. Thank you for starting your search for a Missouri home based franchise with BizQuest!

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No franchises matching your criteria were found, please consider these popular franchises seeking buyers in Missouri.

Assisted Living Locators
Liquid Capital Required:
$50,000

Empower Lives with Assisted Living Locators. Thriving Home-Based Referral and Placement Franchise. Discover Lucrative Opportunities for Business Success Today! More info

Cruise Planners
Liquid Capital Required:
$9,995

For more than 20 years, Cruise Planners has been a low-cost franchise opportunity that can yield high returns! More info

Travelin’ Tom’s Coffee
Liquid Capital Required:
$50,000

Premium mobile coffee franchise from the makers of Kona Ice. Proven model, fixed royalties, and expert business support. Own your journey today! More info

Woof Gang Bakery & Grooming
Liquid Capital Required:
$100,000

"With 450+ locations and average sales of $740k, Woof Gang couples financial opportunity with the chance to build something meaningful. Woof Gang blends high‑end grooming, gourmet treats, and premium pet supplies into a dog‑centric, customer‑friendly haven. With complete training and support for every business decision, we set you up to serve your community, care for pets, and grow a profitable business you’ll love. More info

Pet Wants
Liquid Capital Required:
$50,000

Fresh pet food franchise in a $158B industry. Low investment, proven system, full support. Avg. revenue $546K. No experience needed. More info

ATC Healthcare Services
Liquid Capital Required:
$200,000

If you’ve got business savvy and a passion for helping others, ATC Healthcare Services offers a healthcare staffing agency to take your entrepreneurial spirit to new heights! More info

Molly Maid
Liquid Capital Required:
$60,000

Ranked as a top Residential Cleaning franchise by 2026 Entrepreneur Franchise 500®. 91% recurring customers!* More info

Ace Handyman Services
Liquid Capital Required:
$75,000

Ace Handyman Services, owned by Ace Hardware, is a home services business that focuses on solving customer's small to large size handyman projects in the home and commercial space. More info

First Day Homecare
Liquid Capital Required:
$55,000

The only U.S. franchise in Pediatric Private Duty Nursing plus senior care and ABA. Recurring insurance-funded revenue. From $143,780 More info

A Place At Home
Liquid Capital Required:
$50,000

Build a thriving senior care business with heart. Multiple revenue streams, award-winning support, and a mission that makes a difference. More info

Junk King
Liquid Capital Required:
$50,000

Ranked as a top Junk-Removal Services franchise by 2026 Entrepreneur Franchise 500®. $551K average gross sales!* More info

CEO Life Corporation
Liquid Capital Required:
$200,000

Opportunity for a high margin, recurring revenue, no rent, no working capital, little employees, can be hands on or hands off, over simplistic business, with lots of room for error and hiccups - backed by a growing national team of top entrepreneurs that have already grown 8+ figure businesses, working on a common global mission. More info

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